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교수소개

전임교수

  • 조교수 첨단바이오헬스
  • 이성현
    Lab 미토콘드리아 생명공학 연구실

관심분야

미토콘드리아, 유전자 교정, DNA, 단백질 공학, 생쥐 유전학

학술지 논문

  • (2025)  In vivo mitochondrial base editing restores genotype and visual function in a mouse model of LHON.  NATURE COMMUNICATIONS.  16,  1
  • (2024)  Comprehensive phenotypic assessment of nonsense mutations in mitochondrial ND5 in mice.  EXPERIMENTAL AND MOLECULAR MEDICINE.  1,  1
  • (2024)  Engineering TALE-linked deaminases to facilitate precision adenine base editing in mitochondrial DNA.  CELL.  187,  1
  • (2023)  Counting DNA molecules on a microchannel surface for quantitative analysis.  TALANTA.  252,  123826
  • (2022)  Precision mitochondrial DNA editing with high-fidelity DddA-derived base editors.  NATURE BIOTECHNOLOGY.  41,  3
  • (2022)  Enhanced mitochondrial DNA editing in mice using nuclear-exported TALE-linked deaminases and nucleases.  GENOME BIOLOGY.  23,  1
  • (2022)  Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases.  CELL.  185,  10