Tumor Microenvironment Coordination & Drug Resistance
Drug Discovery against Ocular Diseases
Agonistic CAR-T Cell Therapy
학력
(Ph.D.) College of Pharmacy, Seoul National University (2009)
약력/경력
Postdoctoral Fellow, College of Pharmacy, Seoul National University (2009-2010)
Postdoctoral Fellow, University of Texas, M.D. Anderson Cancer Center (2010-2011)
Full-time Lecturer, Assistant and Associate Professor, College of Pharmacy, Inje University (2011-2020)
Associate Professor, School of Pharmacy, Sungkyunkwan University (2020-present)
학술지 논문
(2025)
Integrating allostasis and emerging technologies to study complex diseases.
COMMUNICATIONS BIOLOGY.
8,
1
(2025)
Flavonoid-based dual modulation of GPR120 and PPARγ: A potential therapeutic strategy for metabolic disease intervention.
BIOORGANIC CHEMISTRY.
164,
(2025)
The patient-specific mouse model with Foxg1 frameshift mutation provides insights into the pathophysiology of FOXG1 syndrome.
Nature Communications.
16,
1
(2025)
Erythromycin stress upregulates anti-angiogenic metabolites in the gut bacterium, Aneurinibacillus aneurinilyticus.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY.
1,
1
(2025)
Metabolic state uncovers prognosis insights of esophageal squamous cell carcinoma patients.
JOURNAL OF TRANSLATIONAL MEDICINE.
23,
1
(2024)
Gut Bacterial Metabolites from Tryptophan and Phenylalanine Induce Melatonin Synthesis and Extend Sleep Duration in Mice.
ACS OMEGA.
9,
43
(2024)
Collagenase and Tyrosinase Inhibitory Compounds from Fish Gut Bacteria Ruegeria atlantica and Pseudoalteromonas neustonica.
ACS OMEGA.
9,
32
(2024)
Structural Diversification of Pyrazinone Metabolites via Spontaneous Oxa-Michael Addition in Staphylococcus xylosus.
JOURNAL OF NATURAL PRODUCTS.
87,
7
(2024)
Particulate matter-induced metabolic recoding of epigenetics in macrophages drives pathogenesis of chronic obstructive pulmonary disease.
JOURNAL OF HAZARDOUS MATERIALS.
464,
(2023)
Ginsenoside Re inhibits melanogenesis and melanoma growth by downregulating microphthalmia-associated transcription factor.
BIOMEDICINE & PHARMACOTHERAPY.
165,
(2023)
The tobacco-specific carcinogen NNK induces pulmonary tumorigenesis via nAChR/Src/STAT3-mediated activation of the renin-angiotensin system and IGF-1R signaling.
EXPERIMENTAL AND MOLECULAR MEDICINE.
55,
6
(2023)
Discovery and Biosynthesis of Imidazolium Antibiotics from the Probiotic Bacillus licheniformis.
JOURNAL OF NATURAL PRODUCTS.
86,
4
(2022)
miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1.
CELL DEATH AND DIFFERENTIATION.
29,
6
(2022)
Ninjurin1 drives lung tumor formation and progression by potentiating Wnt/beta-Catenin signaling through Frizzled2-LRP6 assembly.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH.
41,
1
(2022)
An aqueous extract from Artemisia capillaris inhibits acute gastric injury through mucosal stabilization.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE.
102,
3
(2022)
Preventive effects of cristacarpin on experimentally induced uveitis by targeting NF-kappa B.
BIOMEDICINE & PHARMACOTHERAPY.
145,
-
(2021)
Claudin-5a knockdown attenuates blood-neural barrier in zebrafish.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY.
250,
109176
(2021)
Enhanced anti-angiogenic activity of novel melatonin-like agents.
JOURNAL OF PINEAL RESEARCH.
71,
1
Nitraria Alkaloid 유도체를 포함하는 혈관신생 예방 또는 치료용 조성물.
10-2002-0094063.
20250730.
대한민국
각막 손상 또는 안구건조증 예방 또는 치료용 조성물.
10-2021-0177106.
20250328.
대한민국
사이클로헥사논 또는 사이클로헥사놀 유도체를 포함하는 대사성 질환 예방 또는 치료용 조성물.
10-2021-0144093.
20241106.
대한민국
마이크로 RNA를 유효성분으로 함유하는 Ninj1 억제용 시약조성물(Reagent composition for inhibiting Ninj1 comprising microRNA).
10-2095-2980000.
20200325.
대한민국
신규한 이소나이트라민 화합물 및 이를 포함하는 대사성 질환 예방 또는 치료용 조성물(Novel Isonitramine Compound and Composition for Preventing or Treating Metabolic Disease Comprising the Same).
16161094.
20200121.
미국
알파-휴물렌(alpha-Humulene)을 유효성분으로 포함하는 소화기계 점막 관련 질환 예방 또는 치료용 조성물(Composition Comprising alpha-Humulene for Preventing or Treating Diseases Associated with Mucous Membrane of Digestive System).
10-2043-8930000.
20191106.
대한민국
알파-휴물렌을 유효성분으로 함유하는 안구 건조증 예방 또는 치료용 조성물(Compositions for Preventing or Treating Dry Eye Syndrome Comprising Alpha-humulene).
10-2040-8100000.
20191030.
대한민국
홍합패각 및 올리고당을 유효성분으로 함유하는 칼슘복합제 및 이의 용도(Calcium complex comprising mussel shell and oligosaccharide and uses thereof).
10-2040-8090000.
20191030.
대한민국
신규한 이소나이트라민 화합물 및 이를 포함하는 대사성 질환 예방 또는 치료용 조성물(Novel Isonitramine Compound and Composition for Preventing or Treating Metabolic Disease Comprising the Same).
10-1799-7930000.
20171115.
대한민국
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