"My research is all about big data" to address basic science questions that inform on human diseases and ultimately diagnostic, prognostic and therapeutic applications in personalized medicine.
학력
PhD, Columbia University, New York
MS, University of Michigan, Ann Arbor
BS, Korea University, Seoul
약력/경력
Affiliate Scientist, The Jackson Laboratory for Genomic Medicine, 2021 ~ Present
Senior Research Scientist, The Jackson Laboratory for Genomic Medicine, 2016 ~ 2021
Research Faculty, MD Anderson Cancer Center, 2015 ~ 2016
Postdoc Fellow, MD Anderson Cancer Center, 2021 ~ 2015
Research Assistant, Columbia University, 2006 ~ 2010
Research Intern, Philips Research North America, 2009
Telecommunication System Engineer, LG Electronics Inc., 2000 ~ 2002
학술지 논문
(2026)
IDH-mutant gliomas arise from glial progenitor cells harboring the initial driver mutation.
SCIENCE.
391,
6781
(2025)
Extrachromosomal DNA amplifications exhibit distinct molecular characteristics and prognostic implications in gastric cancer.
CANCER LETTERS.
639,
2026
(2025)
EGFR-targeted micelles-in-lipopolymersome nanocarriers for overcoming drug resistance in triple-negative breast cancer.
JOURNAL OF MATERIALS CHEMISTRY B.
2025,
13
(2025)
Spatial and genomic profiling of residual breast cancer after neoadjuvant chemotherapy unveil divergent fates for each breast cancer subtype.
CELL REPORTS MEDICINE.
6,
6
(2024)
Association of higher potency statin use with risk of osteoporosis and fractures in patients with stroke in a Korean nationwide cohort study.
SCIENTIFIC REPORTS.
14,
1
(2024)
Mapping extrachromosomal DNA amplifications during cancer progression.
NATURE GENETICS.
56,
11
(2023)
Extrachromosomal DNA in the cancerous transformation of Barrett's oesophagus.
NATURE.
616,
7958
(2023)
Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma.
Neoplasia (United States).
36,
(2023)
Elevated IFNA1 and suppressed IL12p40 associated with persistent hyperinflammation in COVID-19 pneumonia.
FRONTIERS IN IMMUNOLOGY.
14,
(2022)
Glioma progression is shaped by genetic evolution and microenvironment interactions.
CELL.
185,
12
(2021)
Live-Cell Imaging Shows Uneven Segregation of Extrachromosomal DNA Elements and Transcriptionally Active Extrachromosomal DNA Hubs in Cancer.
CANCER DISCOVERY.
12,
2
(2021)
Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response.
NATURE GENETICS.
53,
10
(2021)
Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription.
CANCER CELL.
39,
5
수상/공훈
Caroline Ross Endowed Fellowship Award, MD Anderson Cancer Center, 2015
Odyssey Fellowship Award, MD Anderson Cancer Center, 2012‐2014
발전기금
