Drug Delivery, Nanoparticles, Lipid Nanoparticle (LNP), mRNA Delivery, Hybrid Materials, Cancer Immunotherapy, Biomedical Imaging, Cell Engineering, Medical Devices
학력
(2015, Ph.D.) Department of Biotechnology, The Catholic University of Korea
(2008, B.S.) Department of Biotechnology, The Catholic University of Korea
약력/경력
(2022 ~ Present) Assistant Professor, Department of Integrative Biotechnology, Sungkyunkwan University, Republic of Korea
(2020 ~ 2022) Assistant Professor, Department of Biomedical Chemical Engineering, The Catholic University of Korea
(2017 ~ 2020) Assistant Professor, Department of Biomedical Science, College of Life Sciences, CHA University, Republic of Korea
(2015 ~ 2017) Research Associate (Postdoctoral fellow), Department of Radiology, Northwestern University Feinberg School of Medicine, USA
학술지 논문
(2026)
Biomimetic lipid nanoparticles for macrophage reprogramming in cancer immunotherapy.
JOURNAL OF CONTROLLED RELEASE.
1,
1
(2026)
Biomimetic Nanogels Programmed for Irreversible Electroporation-Primed Tumor Microenvironments to Elicit Durable Anti-Tumor Immunity.
BIOMATERIALS RESEARCH.
1,
1
(2026)
Synergistic immunotherapeutic effects of irreversible electroporation and CAR-NK cell therapy against hepatocellular carcinoma.
SIGNAL TRANSDUCTION AND TARGETED THERAPY.
11,
86
(2026)
Transforming Lipid Nanoparticles into Radio-Activatable Therapeutics Through Synergistic Ferroptosis for Enhanced Cancer Radiotherapy.
BIOMATERIALS.
330,
(2025)
Photosensitizing Lipid Nanoparticles for Ferroptosis-Enhanced Photodynamic Cancer Therapy via GPX4 Silencing.
ADVANCED HEALTHCARE MATERIALS.
1,
1
(2025)
Advanced nanoparticle therapeutics for targeting neutrophils in inflammatory diseases.
ADVANCED HEALTHCARE MATERIALS.
14,
28
(2025)
Lipid nanoparticles target neutrophils to reduce SARS-CoV-2-induced lung injury and inflammation.
JOURNAL OF CONTROLLED RELEASE.
382,
1
(2025)
Joule-Assisted Nanotherapeutic Urethral Stent (JANUS) for Spatiotemporal Theragenerative Treatment of Urethral Strictures.
ADVANCED FUNCTIONAL MATERIALS.
1,
1
(2025)
Sequential nanoparticle therapy targeting neutrophil hyperactivation to prevent neutrophil-induced pulmonary fibrosis.
JOURNAL OF NANOBIOTECHNOLOGY.
23,
1
(2025)
Dual-Functional Hafnium Oxide Nanoplatform Combining High-Z Radiosensitization with Bcl-2 Gene Silencing for Enhanced Cancer Radiotherapy.
ADVANCED HEALTHCARE MATERIALS.
1,
1
(2025)
Lung-homing nanoliposomes for early intervention in NETosis and inflammation during acute lung injury.
NANO CONVERGENCE.
12,
8
(2024)
Engineered Cell-Derived Nanovesicles with CAR and PH20 for Enhanced Targeted Photodynamic Cancer Therapy and Tumor Microenvironment Modulation.
ADVANCED FUNCTIONAL MATERIALS.
1,
1
(2024)
An electro-ferroptotic nanoammunition enables image-guided, spatiotemporally controlled cancer ferroptosis induction via irreversible electroporation.
CHEMICAL ENGINEERING JOURNAL.
487,
(2024)
Enhanced Postsurgical Cancer Treatment Using Methacrylated Glycol Chitosan Hydrogel for Sustained DNA/Doxorubicin Delivery and Immunotherapy.
BIOMATERIALS RESEARCH.
28,
1
(2024)
Enhancing CAR-NK Cells Against Solid Tumors Through Chemical and Genetic Fortification with DOTAP-Functionalized Lipid Nanoparticles.
ADVANCED FUNCTIONAL MATERIALS.
1,
1
(2024)
M1-polarized macrophage-derived cellular nanovesicle-coated lipid nanoparticles for enhanced cancer treatment through hybridization of gene therapy and cancer immunotherapy.
ACTA PHARMACEUTICA SINICA B.
1,
1
(2023)
Anti-Inflammatory Artificial Extracellular Vesicles with Notable Inhibition of Particulate Matter-Induced Skin Inflammation and Barrier Function Impairment.
ACS APPLIED MATERIALS & INTERFACES.
15,
51
(2023)
3D-printed NIR-responsive bullets as multifunctional nanodrug platforms for image-guided local chemo-photothermal therapy.
CHEMICAL ENGINEERING JOURNAL.
477,
(2023)
Lipid nanoparticle-based mRNA delivery systems for cancer immunotherapy.
NANO CONVERGENCE.
10,
1
(2023)
The ELK3-DRP1 axis determines the chemosensitivity of triple-negative breast cancer cells to CDDP by regulating mitochondrial dynamics.
CELL DEATH DISCOVERY.
9,
1
수상/공훈
(2021) PHI BIOMED Young Scientist Award, Korean Society for Biomaterials
(2021) MIWON COMMERCIAL Young Scientist Award, The Korean Society of Industrial and Engineering Chemistry
(2020) MEDIPOST Young Scientist Award Korean, Korean Tissue Engineering and Regenerative Medicine Society
(2013) Korean and Japanese Biomaterials Societies Young Scientist Exchange Program Award, The Korean and Japanese Society for Biomaterials
발전기금
