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교수소개

전임교수

  • 부교수 바이오의약품 전달
  • 박우람
    Lab 첨단바이오의약품전달 연구실

관심분야

Drug Delivery, Nanoparticles, Lipid Nanoparticle (LNP), mRNA Delivery, Hybrid Materials, Cancer Immunotherapy, Biomedical Imaging, Cell Engineering, Medical Devices

학력

  • (2015, Ph.D.) Department of Biotechnology, The Catholic University of Korea
  • (2008, B.S.) Department of Biotechnology, The Catholic University of Korea

약력/경력

  • (2022 ~ Present) Assistant Professor, Department of Integrative Biotechnology, Sungkyunkwan University, Republic of Korea
  • (2020 ~ 2022) Assistant Professor, Department of Biomedical Chemical Engineering, The Catholic University of Korea
  • (2017 ~ 2020) Assistant Professor, Department of Biomedical Science, College of Life Sciences, CHA University, Republic of Korea
  • (2015 ~ 2017) Research Associate (Postdoctoral fellow), Department of Radiology, Northwestern University Feinberg School of Medicine, USA

학술지 논문

  • (2026)  Transforming Lipid Nanoparticles into Radio-Activatable Therapeutics Through Synergistic Ferroptosis for Enhanced Cancer Radiotherapy.  BIOMATERIALS.  330, 
  • (2025)  Photosensitizing Lipid Nanoparticles for Ferroptosis-Enhanced Photodynamic Cancer Therapy via GPX4 Silencing.  ADVANCED HEALTHCARE MATERIALS.  1,  1
  • (2025)  Advanced nanoparticle therapeutics for targeting neutrophils in inflammatory diseases.  ADVANCED HEALTHCARE MATERIALS.  14,  28
  • (2025)  Lipid nanoparticles target neutrophils to reduce SARS-CoV-2-induced lung injury and inflammation.  JOURNAL OF CONTROLLED RELEASE.  382,  1
  • (2025)  Joule-Assisted Nanotherapeutic Urethral Stent (JANUS) for Spatiotemporal Theragenerative Treatment of Urethral Strictures.  ADVANCED FUNCTIONAL MATERIALS.  1,  1
  • (2025)  Sequential nanoparticle therapy targeting neutrophil hyperactivation to prevent neutrophil-induced pulmonary fibrosis.  JOURNAL OF NANOBIOTECHNOLOGY.  23,  1
  • (2025)  Dual-Functional Hafnium Oxide Nanoplatform Combining High-Z Radiosensitization with Bcl-2 Gene Silencing for Enhanced Cancer Radiotherapy.  ADVANCED HEALTHCARE MATERIALS.  1,  1
  • (2025)  Lung-homing nanoliposomes for early intervention in NETosis and inflammation during acute lung injury.  NANO CONVERGENCE.  12,  8
  • (2024)  Engineered Cell-Derived Nanovesicles with CAR and PH20 for Enhanced Targeted Photodynamic Cancer Therapy and Tumor Microenvironment Modulation.  ADVANCED FUNCTIONAL MATERIALS.  1,  1
  • (2024)  An electro-ferroptotic nanoammunition enables image-guided, spatiotemporally controlled cancer ferroptosis induction via irreversible electroporation.  CHEMICAL ENGINEERING JOURNAL.  487, 
  • (2024)  Enhanced Postsurgical Cancer Treatment Using Methacrylated Glycol Chitosan Hydrogel for Sustained DNA/Doxorubicin Delivery and Immunotherapy.  BIOMATERIALS RESEARCH.  28,  1
  • (2024)  Enhancing CAR-NK Cells Against Solid Tumors Through Chemical and Genetic Fortification with DOTAP-Functionalized Lipid Nanoparticles.  ADVANCED FUNCTIONAL MATERIALS.  1,  1
  • (2024)  M1-polarized macrophage-derived cellular nanovesicle-coated lipid nanoparticles for enhanced cancer treatment through hybridization of gene therapy and cancer immunotherapy.  ACTA PHARMACEUTICA SINICA B.  1,  1
  • (2023)  Anti-Inflammatory Artificial Extracellular Vesicles with Notable Inhibition of Particulate Matter-Induced Skin Inflammation and Barrier Function Impairment.  ACS APPLIED MATERIALS & INTERFACES.  15,  51
  • (2023)  3D-printed NIR-responsive bullets as multifunctional nanodrug platforms for image-guided local chemo-photothermal therapy.  CHEMICAL ENGINEERING JOURNAL.  477, 
  • (2023)  Lipid nanoparticle-based mRNA delivery systems for cancer immunotherapy.  NANO CONVERGENCE.  10,  1
  • (2023)  The ELK3-DRP1 axis determines the chemosensitivity of triple-negative breast cancer cells to CDDP by regulating mitochondrial dynamics.  CELL DEATH DISCOVERY.  9,  1
  • (2023)  Systemic Delivery of a STING Agonist-Loaded Positively Charged Liposome Selectively Targets Tumor Immune Microenvironment and Suppresses Tumor Angiogenesis.  SMALL.  19,  43
  • (2023)  Uniform Gold Nanostructure Formation via Weakly Adsorbed Gold Films and Thermal Annealing for Reliable Localized Surface Plasmon Resonance-Based Detection of DNase-I.  SMALL.  19,  39
  • (2023)  Multifunctional porous microspheres encapsulating oncolytic bacterial spores and their potential for cancer immunotherapy.  BIOMATERIALS SCIENCE.  11,  13

수상/공훈

  • (2021) PHI BIOMED Young Scientist Award, Korean Society for Biomaterials
  • (2021) MIWON COMMERCIAL Young Scientist Award, The Korean Society of Industrial and Engineering Chemistry
  • (2020) MEDIPOST Young Scientist Award Korean, Korean Tissue Engineering and Regenerative Medicine Society
  • (2013) Korean and Japanese Biomaterials Societies Young Scientist Exchange Program Award, The Korean and Japanese Society for Biomaterials