Skin physiology & Signal transduction,
Skin diseases & Immunology,
Cancer research (melanoma, prostate cancer, etc.)
Development of functional agents for abnormal skin conditions,
학력
(Ph.D.) Dept. of Pharmaceutics, Seoul National University
약력/경력
2022.03 ~ present: Dept. of Integrative Biotechnology, Sungkyunkwan University (Status: Professor)
2016.03 ~ 2022.02: Dept. of Integrative Biotechnology, Sungkyunkwan University (Status: Associate Professor)
2015.09 ~ 2016.02: Dept. of Genetic engineering, Sungkyunkwan University (Status: Assistant Professor)
2012.03 ~ 2015.08: Dept. of Dermatological Health Management, Eulji University (Status: Assistant Professor)
2002.03 ~ 2012.02: Biospectrum Life Science Institute (Status: Research Director)
1995.12 ~ 2001.05: Mogam Biotechnology Research Institute (Status: Senior Research Scientist)
2015.04 ~ Present: Journal of Ginseng Research (SCIE) (Status: Associate editor)
학술지 논문
(2025)
The ectopic olfactory receptor OR7A17 regulates the proliferation and differentiation of human epidermal keratinocytes, and ginsenoside Rh3 acts as its antagonist.
JOURNAL OF GINSENG RESEARCH.
50,
2
(2025)
Roridin E and satratoxin H, macrocyclic trichothecene mycotoxins, induce endoplasmic reticulum stress-dependent apoptosis through ribosome interaction in B16 mouse melanoma cells.
BIOORGANIC CHEMISTRY.
164,
1
(2025)
The Role of MRGPRX1 in the Melanogenesis of Human Primary Epidermal Melanocytes.
JOURNAL OF INVESTIGATIVE DERMATOLOGY.
S0022-202X,
25
(2025)
An AAQPR peptide from Aspergillus oryzae-fermented wheat peptone promotes the regenerative potential of dermal and epidermal layers of the skin in in vitro assays and clinical trials.
BIOMATERIALS SCIENCE.
13,
15
(2025)
Therapeutic potential of ginsenosides in circadian rhythm-based skin disorders.
JOURNAL OF GINSENG RESEARCH.
49,
4
(2025)
Ammonium chloride, an environmental pollutant, disrupts melanocyte biology through the regulation of melanosome and autophagy.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.
296,
1
(2025)
Protective effect of melatonin against blue light-induced cell damage via the TRPV1–YAP pathway in cultured human epidermal keratinocytes.
BIOFACTORS.
51,
2
(2024)
The Pigmentation of Blue Light Is Mediated by Both Melanogenesis Activation and Autophagy Inhibition through OPN3–TRPV1.
JOURNAL OF INVESTIGATIVE DERMATOLOGY.
2024,
9
(2024)
Anti-pollutant effect of oleic acid against urban particulate matter is mediated via regulation of AhR- and TRPV1-mediated signaling in vitro.
ENVIRONMENTAL TOXICOLOGY.
39,
6
(2023)
Protection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesis.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES.
19,
12
(2023)
The relationship of skin disorders, COVID-19, and the therapeutic potential of ginseng: a review.
JOURNAL OF GINSENG RESEARCH.
47,
1
(2022)
Antioxidant Activities and Mechanisms of Tomentosin in Human Keratinocytes.
ANTIOXIDANTS.
11,
5
(2021)
Olfactory Receptor OR7A17 Expression Correlates with All-Trans Retinoic Acid (ATRA)-Induced Suppression of Proliferation in Human Keratinocyte Cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
22,
22
(2021)
Protective Effects of Maclurin against Benzo[a]pyrene via Aryl Hydrocarbon Receptor and Nuclear Factor Erythroid 2-Related Factor 2 Targeting.
ANTIOXIDANTS.
10,
8
(2021)
Pharmacological potential of ginseng and its major component ginsenosides.
JOURNAL OF GINSENG RESEARCH.
45,
2
(2021)
Spermidine-induced recovery of human dermal structure and barrier function by skin microbiome.
COMMUNICATIONS BIOLOGY.
4,
1
(2021)
The Role of Leptin in the Association between Obesity and Psoriasis.
BIOMOLECULES THERAPEUTICS.
29,
1
(2020)
The Role of Autophagy in Skin Fibroblasts, Keratinocytes, Melanocytes, and Epidermal Stem Cells..
JOURNAL OF INVESTIGATIVE DERMATOLOGY.
140,
9
(2020)
Pyropia YezoensisExtract Suppresses IFN-Gamma- and TNF-Alpha-Induced Proinflammatory Chemokine Production in HaCaT Cells via the Down-Regulation of NF-kappa B.
NUTRIENTS.
12,
5
(2020)
The Role of Autophagy in Skin Fibroblasts, Keratinocytes, Melanocytes, and Epidermal Stem Cells.
JOURNAL OF INVESTIGATIVE DERMATOLOGY.
140,
9
특허/프로그램
유전자 발현 측정을 통한 외부자극 완화 효능 평가방법.
10-2018-0053848.
20191015.
대한민국
학술회의논문
(2019)
Melanogenic effects of Blue Light are mediated by Clusterin and Ca2+ influx.
25th IFSCC.
EU연합
(2019)
Nrf2-mediated defense mechanisms against PM-induced oxidative stress in keratinocytes.
25th IFSCC.
EU연합
(2019)
Protective Effect of Material X against Benzo[a]pyrene-Induced DNA Damage and oxidative stress in keratinocyte cell line.
25th IFSCC.
EU연합
(2019)
Effects of blue-light irradiation on human keratinocytes are mediated via transient receptor potential vanilloid (TRPV)-1-mediated signaling.
대한생리학회.
대한민국
(2019)
p44/42 MAPK signaling is a prime target activated by phenylethyl resorcinol in its anti-melanogenic action.
XXIIIth International Congress"Phytopharm 2019".
러시아
(2017)
Stemness and differentiation potential-recovery effects of sinapic acid against ultraviolet-A-induced damage through the regulation of p38 MAPK and NF-κB.
47th Annual ESDR Meeting.
오스트리아
(2016)
Biochanin A promotes melanogenesis through cAMP signaling pathway in B16F10 melanoma cells.
2016 International Conference of the Korean Society for Molecular and Cellular Biology.
대한민국
(2016)
Involvement of cAMP and MAPKs signaling in resorcinol-reduced melanogenesis of B16F10 mouse melanoma cells.
2016 International Conference of the Korean Society for Molecular and Cellular Biology.
대한민국
(2016)
Vanillin attenuates negative effects of Ultraviolet A on the stemness of human adipose tissue-derived mesenchymal stem cells.
Journal of Investigative Dermatology (46th Annual ESDR Meeting).
독일
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