(2023)
Three-dimensional human neural culture on a chip recapitulating neuroinflammation and neurodegeneration.
NATURE PROTOCOLS.
18,
9
(2023)
Astrocytic scar restricting glioblastoma via glutamate-MAO-B activity in glioblastoma-microglia assembloid.
BIOMATERIALS RESEARCH.
27,
1
(2022)
Human mini-blood-brain barrier models for biomedical neuroscience research: a review.
BIOMATERIALS RESEARCH.
26,
1
(2022)
Nanomedicine for advanced cancer immunotherapy.
JOURNAL OF CONTROLLED RELEASE.
351,
-
(2022)
Neuroinflammation in neurodegeneration via microbial infections.
FRONTIERS IN IMMUNOLOGY.
13,
-
(2022)
Adipokine human Resistin promotes obesity-associated inflammatory intervertebral disc degeneration via pro-inflammatory cytokine cascade activation.
SCIENTIFIC REPORTS.
12,
1
(2022)
TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia.
ELIFE.
11,
-
(2021)
An Air Particulate Pollutant Induces Neuroinflammation and Neurodegeneration in Human Brain Models.
ADVANCED SCIENCE.
8,
21
(2021)
Oral Pathogenic Bacteria-Inducing Neurodegenerative Microgliosis in Human Neural Cell Platform.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
22,
13
(2021)
Human brain organoids in Alzheimer’s disease.
Organoid.
1,
1
(2021)
Time-Dependent Internalization of Polymer-Coated Silica Nanoparticles in Brain Endothelial Cells and Morphological and Functional Effects on the Blood-Brain Barrier.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
22,
4
(2021)
Human mini-brain models.
NATURE BIOMEDICAL ENGINEERING.
5,
1
(2020)
Therapeutic Targeting Strategies for Early- to Late-Staged Alzheimer's Disease.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
21,
24
(2020)
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2- production.
NATURE NEUROSCIENCE.
23,
12
(2020)
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.
NATURE COMMUNICATIONS.
11,
1
(2019)
Electrical impulse effects on degenerative human annulus fibrosus model to reduce disc pain using micro-electrical impulse-on-a-chip.
SCIENTIFIC REPORTS.
9,
수상/공훈
Best award by Ministry of Science and ICT (2025);
National R&D Top 100 awarded by Ministry of Science and ICT (2024);
National R&D Top 30 by Ministry of Health and Welfare (2024);
Certificate for ‘Best Laboratory of Safety Management’ from the Korea government (2022, 2024);
Junior Faculty Award by Association of Korean Neuroscientists (2018);
Seed grant by Center for Biomedical Engineering and Science (2016, 2017);
Targeted Research Internal Seed Program by Charlotte Research Institute (2017);
Cure Alzheimer’s Fund awards (2015, 2016, 2017, 2018);
Duke Energy Special Initiatives Funding awards by Charlotte Research Institute (2014);
US-Korea conference 2012 young generation fellow (2012);
MGH-ORCD research fellow’s poster celebration award of ‘Poster of Distinction’ (2012);
Korean-American professional community in biotechnology and pharmaceuticals (KASBP)-Green Cross Fellowship (2011);
The first place in the Bears Breaking Boundaries competition under the category of Neglected Diseases (2008);
Lawrence scholar program fellowship (former SEGREF) from Lawrence Livermore National Laboratory (2007);
Fellowship supported by Intel Inc. (2005);
Scholarship supported by the Korea research foundation grant funded by the Korea government (MOEHRD) (2005);
Graduation with cum laude from Seoul National University (1996)
학술회의논문
(2022)
Fine particulate matter in air pollutants promotes neuroinflammation and exacerbates tauopathy in human minibrain.
2022 Int'l Conference on Alzheimer’s and Parkinson’s Diseases and related neurological disorders.
스페인
(2022)
Air particulate pollutant inducing neurodegenerative inflammation,” 3rd International Webinar on Dementia and Alzheimer Rehabilitation.
3rd International Webinar on Dementia and Alzheimer Rehabilitation.
영국
(2022)
Human 3D Mini-Brain Model for the Study of Neurological Disorders.
2022년 한국뇌신경과학회 신경교세포분과 정기학술대회.
대한민국
(2021)
Oral Pathogenic Bacteria-Inducing Neurodegenerative Microgliosis in Human Neural Cell Platform.
5th International Webinar on Global Advanced Nursing, Patient Safety and Healthcare.
영국
(2021)
Glial Scar Causing Drug Resistance and Inhibiting Glioblastoma Growth in a 3D Human Glioblastoma Microenvironment.
the Society for Neuroscience’s annual meeting 2021.
미국
(2021)
Organoid Standardization, Clinical Application and Regeneration.
International Conference of the Organoid Society 2021.
대한민국
(2021)
Construction of 3D Glial Scared-GBM Microenvironment and increase of Drug Sensitivity by KDS20210.
INTERNATIONAL SYMPOSIUMON REACTIVE ASTROCYTES AND GLIOBLASTOMA.
대한민국
(2021)
From disease research to successful commercialization based on organoids.
Organoid Bench to Business Symposium 2021.
대한민국
(2021)
Construction of in vitro Human Brain Models.
오가노이드 미니심포지엄 2021.
대한민국
(2020)
Assessment of neurodegenerative microgliosis induced by oral pathogenic bacteria.
Neurodegenerative Diseases: Biology & Therapeutics.
미국
(2020)
3D Human Brain models in Microfluidics for the Study of Neurological Disorders.
제1회 바이오융합세미나.
대한민국
(2019)
3D human brain model in Alzheimer’s disease.
2019 한국바이오칩학회 추계학술대회.
대한민국
(2019)
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via excessive H2O2-production.
the 10th World Congress of Neuroscience.
대한민국
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